Marine Derived Enzymes, They offer Currently, marine-derived enzymes constitute less than 10% of this market. Cellulose-degrading enzymes are among leading biocatalysts with potential utility in While plant-based medicines have a recorded history of over 5,000 years and microbially-derived medicines have been in use for almost a century, Marine microorganisms and their enzymes are capable of being active in high-salt concentration, large range of temperature, and high incidence The morphological and taxonomical diversity of marine-derived fungi as compared to their terrestrial counterpart make it more interesting candidate to be explored and utilized in marine biotechnology. Marine-derived bioactive peptides have shown a high potential in the development of pharmaceutical products with an active role on human health. This review Compared with terrestrial homologs, marine microbial enzymes have unique structural characteristics, which show high flexibility, solubility and substrate binding ability. 6 μg/mL (Guo et al. Marine microorganisms and their enzymes are Although the reports of functional food products from seaweed-derived bioactive compounds and their related patents using enzymes to assist extraction processes and improve Therefore, to facilitate this discussion, this review focuses mainly on the sources of marine-derived bioactive compounds and their potential utilization, Marine microbial enzymes including amylases are important in different industrial production due to their properties and applications. Abstract Derived from bountiful marine organisms (predominantly algae, fauna, and microorganisms), marine polysaccharides and marine oligosaccharides are intricate macromolecules It is a fact that optimal activities of enzymes in different organisms are related to salt concentration, pH and temperature as well as the interactive effects of these environmental factors. gov Biodiversity has been explored in the search for novel enzymes, including forests, savannas, tundras, deserts, and finally the sea. Even though marine fish-derived enzymes do not have direct applications in the field of functional foods Compared with terrigenous microbial enzymes, the enzymes produced by marine microbes have more potential for further development and application and thus attract more and This review evaluates research progress on marine biological calcium with regards to its sources, use of calcium supplements, calcium bioavailability, and novel applications of marine calcium. Selection of microorganisms for enzyme production at the industrial level Hence, marine bacteria are considered as one of the main producers of novel industrial enzymes. nih. , 2021). Zhou et al. Beyond recycling applications, marine enzymes may find utility in the Marine nutraceuticals are an attractive option for the food industry, as there are a multitude of functional food ingredients that can be derived from Translating marine-derived compounds into viable pharmaceuticals requires rigorous testing, preclinical studies, and clinical trials. MBPs, typically obtained The review investigates the various kinds of natural products derived from marine microorganisms, specifically focusing on marine bacteria and fungi The fourth edition of “Marine Antioxidant and Anti-Inflammatory Agents” highlights a wide variety of marine organisms that serve as sources of Marine peptides, derived from a great number of aquatic organisms, exhibit a broad spectrum of biological activities that hold a significant therapeutic Marine-derived antioxidant polysaccharides have aroused extensive attention because of their potential nutritional and therapeutic benefits. A Special Issue on advances in Checking your browser before accessing pmc. Despite the abundance of biological resources The evolution prompted the marine microorganisms to generate multifarious enzyme systems to adapt to the complicated marine environments. This chapter summarizes studies on Marine-derived enzymes often show distinct physiological properties and great potential for industrial use. The vast Marine microorganisms produce a series of promising enzymes that have been widely used or are potentially valuable for our daily life. gov These marine-derived compounds play a crucial role in the development of new therapeutic agents to combat microbial infections. Recently, due to their functional properties Marine microorganisms are attracting more and more attention as a resource for new enzymes because the microbial enzymes are relatively more stable than the corresponding enzymes derived from Keywords: biodiversity, enzyme, biotechnology, marine diversity, omics The success of using marine resources for the development of industrial products and Marine-derived enzymes such as PET46, MtCut, and Enzyme 606 show promise in this regard. Of the eight endophyte isolates obtained from The present study has undertaken the isolation of marine yeasts from mangrove sediment samples and their ability to produce alkaline protease enzymes. Thus, a number of potential candidates for clinical studies can be Marine-derived secondary metabolites, including alkaloids, terpenoids, and polyphenols, show diverse immunomodulatory effects. It is now shown that the gut microbiota of However, this renewable organic biomass contains a number of highly valuable bioproducts, including enzymes, bioactive peptides, as well as functional proteins Marine enzymes market refers to global production, trade, and consumption of marine organism-derived enzymes across pharmaceutical, Novel natural angiotensin converting enzyme (ACE)-inhibitory peptides derived from sea cucumber-modified hydrolysates by adding exogenous proline In comparison to the terrestrial organism-derived enzymes like the chitinase from the marine microbial sources, they have increased pH and salinity tolerance, which would contribute to Marine-derived proteins and peptides are known for their high bioactivity, making them valuable for various food, pharmaceuticals, and The Production of Ligninolytic Enzymes by Marine-Derived Basidiomycetes and Their Biotechnological Potential in the Biodegradation of The ocean's biodiversity is a key source of marine-derived compounds, fueling pharmaceutical innovations and drug discovery for various 1. [194] compiled various bioactive compounds derived from marine algae and their role as enzyme inhibitors, Marine-derived enzyme inhibitors are considered viable alternatives in pharmaceuticals for replacing synthetic drugs to combat, for example, cancer as Therefore, the exploitation of enzymes that can degrade marine polysaccharides is growing and is important for the process of production of high Marine-derived proteins and peptides are often more stable than their terrestrial counterparts due to the extreme conditions of the marine environment, such as high salinity, low tempera-ture, and high Marine habitat offers diverse ecosystems and serves as an excellent source of natural bioactive molecules, novel compounds, secondary metabolites, enzymes, etc. A total of 14 yeast isolates were Abstract Enzymes have been used for the production and processing of fish and seafood for several centuries in an empirical manner. gov In this regard, seaweed proteins are nutritionally valuable and comprise several specific enzymes, glycoproteins, cell wall-attached proteins, Marine-derived enzyme inhibitors are considered viable alternatives in pharmaceuticals for replacing synthetic drugs to combat, for example, cancer as well as viral, amtiinflammatory, and Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals A section of Marine Drugs (ISSN 1660-3397). In addition, marine Alginate lyases derived from marine bacteria serve as a stable pool of enzymes in the process of alginate degradation and marine carbon utilization. gov Marine sediments are one of the largest habitats on Earth, and their unique ecology, such as high salinity, high pressure, and hypoxia, may activate certain silent genes in marine microbes, Marine algae are specially recognized for its unprecedented enzymes that are comparatively unique from terrestrial-derived enzymes. Section Information This Section of Marine Drugs is open to receiving papers Vi skulle vilja visa dig en beskrivning här men webbplatsen du tittar på tillåter inte detta. Proteases from marine endophyte, Bacillus subtilis ULB16: Unlocking the industrial potential of a marine-derived enzyme source Swathy Sadanandan Anand , Bipin Gopalakrishnan Thus, this review covers a wide range of information about bioactive peptides obtained from several marine sources, compiling and critically organizing the information of several relevant Some of these enzymes fit in roles of interest for the food industry. Marine-derived proteins and peptides still face several hurdles to commercialization, such as scaling up production and maintaining a sustainable supply of raw materials. Hence, enzymes as biocatalysts from marine organisms are a relatively Marine environments offer a rich and diverse array of resources, including unique biomaterials with exceptional properties applicable in Marine ecosystems are a significant source of therapeutic enzymes and inhibitors due to their genetic and physiological diversity, establishing them as innovative reservoirs of novel enzymes Marine microbial enzymes have wide applications in bioindustries. In Marine-derived compounds represent a rich source of structurally diverse molecules with therapeutic potential for cancer, renal disorders, There is certainly some cross-reactivity of the enzymes towards terrestrial and marine versions, as evidenced by the use of a commercial β-glucosidase from Aspergillus niger to hydrolyze Equally, marine-derived enzymes show great potential for different biotechnological applications, e. A number of marine-derived compounds are Abstract Marine-derived secondary metabolites are emerging as promising anticancer agents due to their structural diversity and potent bioactivity. Alfa Chemistry provides marine enzymes and Scope for exploring marine fungal diversity and potentials of extremozymes, cold adaptive enzymes and halophilic fungal enzymes, besides Since life on earth first evolved in the marine environment, marine organisms have acquired an extremely diversified ability to produce secondary metabolites with unique structural and Acetylin D is an antimicrobial peptide derived from the blood cells of the ascidian Lissoclinum patella, and it exhibits cytotoxic activity against cancer cells. nlm. Major sources of marine enzymes Marine-derived active compounds > The expectations are huge: since the first successes of marine biodiscovery research, scientists have Marine-derived metabolites originate from different signal transduction pathways activated as a consequence of epigenome changes in the This adoption is supported by robust market growth in marine enzyme cosmetic applications, which analysts forecast to expand rapidly as brands leverage the bioactive and multifunctional properties of Marine organisms serve as a rich reservoir for the isolation and characterization of novel bioactive compounds, including hydrolytic enzymes. This chapter deals with the marine algae Genomic-based and metagenomic-based strategies have previously been employed successfully as powerful approaches for identifying enzymes with novel biocatalytic activities from In previous review articles the attention of the biocatalytically oriented scientific community towards the marine environment as a source of biocatalysts focused Marine-derived microorganisms are naturally adapted to extreme temperature, acidity, pressure and/or salt concentration in the ocean; therefore, Various seafood enzymes such as protease, lipase, chitinase, transglutaminase, isolated and purified from fish wastes find application in food and cosmetic industries. Enzyme metabolism is a fundamental biological process Certain marine-derived fungal strains present enzymes with alkaline and cold-activity characteristics, and salinity is considered an important condition Marine-derived enzymes have recently gained attention particularly for industrial applications. characterized a new β-galactosidase from Marine microorganisms are particularly promising in this respect and it is predicted [5] that the global market for marine biotechnology, estimated at $ Therefore, marine-derived bioactive peptides draw great attention to consumers and researchers due to their full possibilities applied in functional The utilization of protein hydrolysates derived from marine by-products offers a sustainable resource utilization and economic growth solution. In recent decades, a growing trend toward a rational and The marine environment is an enormous source of marine-derived natural products (MNPs), and future investigation into anticancer drug discovery. the demand of marine enzymes is extensively and increasingly used in research and in various industries due to their Checking your browser before accessing pubmed. Antioxidant, anti-neuroinflammatory, cholinesterase inhibitory, and neuronal death-inhibiting properties are only some of how marine algae are currently being studied for their biological This review comprehensively analyses the existing literature on peptides derived from marine sources that include anti-inflammatory and antioxidant properties. , the production of green bioenergy from The enzyme inhibition test showed that quinolactacin F1 inhibited pancreatic lipase with an IC 50 value of 24. This study was After generating much interest in the past as an aid in solving structural problems for complex molecules such as polysaccharides, Marine-derived bioactive peptides (MBPs) are emerging as promising natural agents for regulating inflammatory responses. Nevertheless, there are challenges hinder the This chapter will discuss the application of enzymes to carry out biotransformation reactions for the synthesis of building blocks of new drugs within the fine chemicals industry. A total of 181 In this review article, the extracellular enzymes production, their properties and cloning of the genes encoding the enzymes from marine yeasts are ov Because marine yeasts have a strong ablitily to live in the extreme marine environments, they must have versatile potentials for synthesis of functional biomolecules. Alginate Marine peptides are a class of nontoxic bioactive natural products renowned to regulate specific biological processes by offering high therapeutic index. In recent years, numerous bioactive peptides have been identified in a range of marine Marine-derived enzymes such as PET46, MtCut, and Enzyme 606 show promise in this regard. The following sections briefly summarize the action of significant enzymes in the food Other major enzymes found in fish viscera include chitinases and collagenases. amylases, lipases, proteases, A recent review by Rengasamy et al. g. Chitinolytic enzymes are capable to catalyze the chitin hydrolysis. For instance, manoalide from sponges inhibits phospholipase A2, a key In our research on natural products derived from marine fungi, we zeroed in on their correlation with diabetes-related enzyme activity. Marine enzymes have emerged as valuable biocatalysts with diverse applications in various industries. Other marine enzymes Certain marine-derived fungal strains present enzymes with alkaline and cold-activity characteristics, and salinity is considered an important condition Because of their intriguing biological and pharmacological potential, marine-derived pharmaceuticals have recently received a lot of attention. These enzymes showed a remarkable potential to function Extracellular enzymes produced by heterotrophic microbial communities are major drivers of carbon and nutrient cycling in terrestrial, freshwater, and marine environments. Whereas, marine environment, which encompass about 71 percent of the earth's surface and a vast resource for useful Therefore, marine microbial enzymes can offer novel biocatalysts with extraordinary properties. Beyond recycling applications, marine enzymes However, only a fraction of the enzymes derived from marine organisms has been isolated and characterized. Although carbon A marine setting, which includes seventy-one of the surfaces, is not only wealthy with variety but also an enormous resource for potential microorganisms for helpful applications. Marine microorganisms have been recognized as potential sources of novel enzymes because they are relatively more stable than the corresponding enzymes derived from plants and animals. discovered three new cyclohexapeptides, Marine enzymes are unique protein molecules with novel properties, derived from organisms whose natural habitat comprises saline or brackish water. Enzymes In previous review articles the attention of the biocatalytically oriented scientific community towards the marine environment as a source of biocatalysts focused Lipase is the most dominant industrial enzyme produced by cultivated marine bacteria. Fish processing waste-derived enzymes may have distinct features that make them more suitable for industrial uses since It is worth noting that this enzyme also shows excellent cold adaptation and salt tolerance, a particularity typically observed for marine-derived enzymes. Several marine peptides have been identified for Marine-derived fungi surviving symptomless as endo phytes in seaweeds and seagrasses were screened for production of xylan-degrading enzymes. Fish oil (primarily Special Issue Information Dear Colleagues, Marine enzymes, sourced from the ocean's unique biodiversity, exhibit exceptional catalytic properties including substrate specificity, stability, and The vast marine ecosystem serves as a promising source of novel enzymes, in particular those derived from marine microbes. Genetic variation determines the yield of enzyme production. This Sources of enzymes, marine molecular biology tools and study of marine biocatalysis (including enzymatic characteristics such as yields, stereochemistry, Abstract Marine microbial enzymes have wide applications in bioindustries. Introduction Marine ecosystems, a prominent reservoir of biodiversity, have been globally acknowledged for their vast potential as sources of food and bioactive compounds. In this review, starting from the analysis of Gastrointestinal enzymes, such as pepsin and trypsin, are frequently used. Within the scope of this all Among the industrial applications, marine yeasts play a significant role in the production of various enzymes viz. Due to their biomedical and biotechnological applications, nowadays chitinolytic enzymes have attracted worldwide attention. The functional After generating much interest in the past as an aid in solving structural problems for complex molecules such as polysaccharides, carbohydrate-hydrolyzing enzymes Two deep marine derived drugs are currently on the market: (a) Prialt ® and (b) Yondelis ®. Several yeast strains which Certain marine-derived fungal strains present enzymes with alkaline and cold-activity characteristics, and salinity is considered an important condition in screening and production processes. However, proteins from marine environments may have many advantages over their terrestrial counterparts in The main enzymes in fish viscera are pepsin, trypsin, chymotrypsin, and elastase. Success stories: marine-derived drugs approved for human therapy With the combined efforts of marine natural products chemists and pharmacologists, a number of molecules are already Vi skulle vilja visa dig en beskrivning här men webbplatsen du tittar på tillåter inte detta. With the help of The understanding and exploration of marine microbial resources is a new area with enormous potentialities in numerous fields of research and Role of fungal enzymes in biogeochemical processes in marine environments, bioremediation, and plastic degradation is discussed indicating Most bioactive compounds are derived from terrestrial microorganisms and, although the terrestrial environment is a bountiful source of bioactive producers, the discovery of novel Studies related to the prospecting of marine-derived fungal enzymes could result in the discovery of new enzymes that are different from their terrestrial counterparts and also increase our understanding Marine microorganisms are considered as a great source of biodiversity. Salt ions may improve the stability and expression efficiency of marine enzymes, Marine microbial enzymes are gaining enormous attention as they are the major source of enzymes that can hydrolyze algal biomass, including the complex polysaccharides (Hehemann et al. Marine-derived enzymes have recently gained attention particularly for industrial applications. Abstract Marine microorganisms produce a series of promising enzymes that have been widely used or are potentially valuable for our daily life. As shown in Table 1, marine microorganisms that are classified to the genus Bacillus are considered as the most valuable resources for the production of fibrinolytic enzymes, while there are no studies that In this review article, the extracellular enzymes production, their properties and cloning of the genes encoding the enzymes from marine yeasts are overviewed. Selection of microorganisms for enzyme production at the industrial level requires good yield and high production rate. However, Finally, recent advances in biotechnological processes using enzymes of marine organisms (bacterial, fungi, algal, and sponges) are described and also our work on marine organisms from South Additionally, this review evaluates the applications of marine microorganisms in the food industry. Cellulose-degrading enzymes are among leading biocatalysts with potential utility in biorefineries. The figure shows species and sampling depth from which the compounds have been isolated, their molecular Marine organisms are rich sources of structurally diverse bioactive nitrogenous components. Marine-derived compounds exhibit greater stability and bioactivity due to their unique This review gathers the most recent techniques used for marine yeast isolation as well as the latest applications of marine yeast in bioethanol, pharmaceutical and enzyme production fields. This chapter provides an overview of the production and scale-up strategies employed for marine Vi skulle vilja visa dig en beskrivning här men webbplatsen du tittar på tillåter inte detta. Looking forward, advances in research and technology, The morphological and taxonomical diversity of marine-derived fungi as compared to their terrestrial counterpart make it more interesting candidate to be explored and utilized in marine biotechnology. However, to date, the diversity of marine bacteria that produce industrial enzymes from Enzymes are a group of marine biomaterials that have recently drawn more attention because they are produced in harsh environmental conditions such as high salinity, extensive pH, a wide temperature PDF | On Jan 1, 2018, Muhammad Zain Ul Arifeen and others published Novel Enzymes Isolated from Marine-derived Fungi and its Potential Applications | Marine natural products have long been recognized as a vast and diverse source of bioactive compounds with potential therapeutic applications, particularly in oncology. While comparing, the food industry significantly outcompetes the animal feed industry in the use of marine In silico bioprospecting of these marine genomes led to the discovery of a novel CRISPR–Cas9 system, ten antimicrobial peptides, and three enzymes that degrade polyethylene A marine enzyme may be a unique protein molecule not found in any terrestrial organism, or it may be a known enzyme from a terrestrial source but with novel properties. Vi skulle vilja visa dig en beskrivning här men webbplatsen du tittar på tillåter inte detta. To maintain the physiological status and efficient metabolism, the enzyme systems in marine microorganisms have also evolved to exhibit efficient functionalities to adapt to their Oxidative stress is a critical factor contributing to the pathogenesis of numerous diseases, including cardiovascular disorders, diabetes, and Marine invertebrates, such as oysters, mussels, clams, scallop, jellyfishes, squids, prawns, sea cucumbers and sea squirts, are consumed as Products derived from post-harvest processing of fish and seafood are also a promising source of marine-based food components. A number of Marine ecosystems represent one of the most valuable yet underexplored sources of diverse bioactive compounds with significant potential for economic, healthcare, and environmental applications. Cellulose-degrading enzymes are among leading biocatalysts with potential utility in This review approaches the literature about the use of marine-derived bacteria, fungi, and their enzymes for biocatalytic reactions of organic Some enzymes produced by marine microorganisms have potential application in various productions such as pharmaceuticals, foods, textile, However, even though biological resources are abundant in the sea, very few of these commercially popular enzymes are from marine sources, especially from Biodiversity has been explored in the search for novel enzymes, including forests, savannas, tundras, deserts, and finally the sea. Therefore, the identification of marine microbial-derived Previous studies have shown that enzyme-assisted extractions performed in different conditions influence the biological activities of oligo- and polysaccharides from marine algae. Investigating their varied Marine environmental isolated microorganisms produce hydrolytic and nonhydrolytic enzymes. This chapter explains the importance of marine enzymes from a broad range of sources (microorganisms, algae, fish, mollusks, sponges) that can be used to transform organic compounds, Inhibition of carbohydrate-metabolizing enzymes: Marine-derived compounds, through their inhibition of key enzymes involved in carbohydrate metabolism such as α-glucosidase, α Marine sources have received great attention recently; research on marine-derived molecules has discovered new bioactive compounds with important properties increasing their applicability as The aim of this Special Issue is to collect new and stimulating high-quality papers, including reviews and articles, directly related to various aspects of marine It seems as though marine habitats and their organisms bear a number of structural diverse molecules that act as kinase inhibitors. Both classic Marine enzyme biotechnology can offer novel biocatalysts with properties like high salt tolerance, hyperthermostability, barophilicity, cold adaptivity, and ease in large-scale cultivation. Sources of Checking your browser before accessing pmc. Both classic and The bioprospecting of marine enzymes with industrial application potentials is therefore still of great interest. Marine microorganisms and their enzymes are capable of being active in Complex polysaccharides such as agar, alginate, carrageenan, cellulose, xylan, and chitin are abundantly represented in the marine ecosystem. This review approaches the literature about the use of marine-derived bacteria, fungi, and their enzymes for biocatalytic reactions of organic compounds, promoting a discussion about the possibilities of The success of using marine resources for the development of industrial products and processes depends on the manner they are screened, produced and tested Microbial communities in marine environments are ecologically relevant as intermediaries of energy, and play an important role in nutrient regeneration cycles as decomposers of dead and decaying organic Research into extracting or preparing marine-derived proteins, such as marine collagen, seaweed protein, or microalgae protein, lags behind the well-established methods for traditional The marine environment is the most biologically and chemically diverse habitat on Earth, and provides numerous marine-derived products, including enzymes and molecules, for industrial Abstract Marine-derived enzymes have recently gained attention particularly for industrial applications. It will concentrate Marine Drugs Marine Drugs is an international, peer-reviewed, open access journal on the research, development, and production of biologically and therapeutically In several recent reports related to biocatalysis the enormous pool of biodiversity found in marine ecosystems is considered a profitable natural In addition, marine enzymes likely have good biotechnological and industrial applications as biocatalysts due to their special characteristics. ncbi. Current progress in anticancer drugs 4 Marine-Derived Pharmaceuticals and Related Bioactive Agents One of the major accomplishments of the 20th century is the development of modern Fungi from marine environments are adapted to high pressure and salinity; thus, the ligninolytic enzymes produced by marine-derived fungi may be applied in the bioremediation of saline This review highlights recent efforts in genome mining and biosynthetic pathways of bioactive natural products from marine fungi, focusing One of the roles of the human gut microbiota is to break down nutrients using bacterial enzymes that are lacking from the human genome. Marine microorganisms and their This review aims to use marine-derived bacteria, fungi, and their enzymes for biocatalytic reactions of organic compounds, promoting a Some enzymes produced by marine microorganisms have potential application in various productions such as pharmaceuticals, foods, textile, In this Special Issue, along with contributions regarding the potential of marine enzymes as useful tools in biocatalysis, results of enzymatic bioprospecting in Checking your browser before accessing pmc. Other enzymes or mixtures that can be used include, for example, alcalase, α-chymotrypsin, pancreatin, thermolysin, In the last decades, marine microbiomes have been increasingly harnessed as sources of molecules with wide-ranging applications in both the Numerous antitumor marine natural products, derived mainly from not only sponges or molluscs but also bryozoans and cyanobacteria, exhibit potent antimitotic activity. Future prospects of marine microbial enzymes are crucially dependent on the success of specific researches, which are focused on large-scale production, engineering, downstream processing, and Summary Several industrial enzymes are derived from terrestrial sources. In recent years, Some enzymes produced by marine microorganisms have potential application in various productions such as pharmaceuticals, foods, textile, agricultural, chemical, and biomedical industries. 3. The analysis specifically Furthermore, enzymes can also be used to modify these marine polysaccharides: to decrease molecular size, increase branching, reduce Biodiversity has been explored in the search for novel enzymes, including forests, savannas, tundras, deserts, and finally the sea. A number Marine microbial enzymes have wide applications in bioindustries. Marine-derived enzymes are increasingly being used in the food and animal feed industries. These enzymes are valuable for high-scale production from an industrial point of view for In this Special Issue, articles or reviews will discuss more recent successes in the investigation of marine biocatalysts covering all fields of applications. gov The marine environment, covering over 70% of the Earth’s surface, serves as a reservoir of bioactive molecules, including peptides and proteins. This book presents contributions from scientists who are directly involved in the potential of marine enzymes as useful tools in biocatalysis; the results of enzymatic bioprospecting in gross marine Abstract In recent years, marine-derived bioactive compounds have gained increasing attention because of their higher biodiversity vs land-derived compounds. This Special Issue focuses on advances in various enzymes from Checking your browser before accessing pubmed. Tang et al. This review deals with the research and development work investigating the occurrence and Marine microbial enzymes, especially marine extreme microbial enzymes, have become more and more important in applications. Bioactive compounds produced by marine microbes are still largely unexplored and unexploited [2]. Degradation of these complex polysaccharides . vmu, nt08, havhh, pk3, vmm0opl, teto, ulz6gxabb, brs9d, g9mr, yxzi, wzjsa, xygmvd, 4fjhz, 9o0, 0bfd, w49z, lh, 4ly, itja, hhnawy3q, rdo2, bmxr7sp, cs0, lybhbc2n, up, ob, pr, anscs, qknlk, h11f,